The overall goal of the Rutgers-NYU Investigator Development Core (IDC) is to support and increase the expertise of interdisciplinary scientists, including those from underrepresented backgrounds, to prepare them to conduct innovative and impactful health equity intervention, prevention, and management research on cardiometabolic and mental health outcomes among Asian Americans. Our approach has implications for understanding mechanisms of both health and wellbeing as well as changing how we ‘think about’ and how we ‘do’ research on these topics. Even more importantly, our approach will transform how we create and conduct research with these populations. Such an approach to health equity research will foster multidirectional and transdisciplinary integration of innovative research that has maximal impact on community practice and policy.